Zacopride
Zacopride is a drug that is used in scientific research. It is classified as a 5-HT4 receptor agonist and a 5-HT3 receptor antagonist. Zacopride has been found to have potent antiemetic and prokinetic properties, making it potentially useful in the treatment of conditions such as gastroesophageal reflux disease and irritable bowel syndrome.
Pharmacology[edit | edit source]
Zacopride acts primarily on the serotonin receptors in the gastrointestinal tract. It stimulates the 5-HT4 receptors, which increases the movement of food through the stomach and intestines. At the same time, it blocks the 5-HT3 receptors, which can help to reduce feelings of nausea and vomiting.
Clinical Use[edit | edit source]
While zacopride has shown promise in preclinical studies, it has not yet been approved for use in humans. Further research is needed to determine its safety and efficacy in the treatment of gastrointestinal disorders.
See Also[edit | edit source]
- 5-HT4 receptor
- 5-HT3 receptor
- Gastrointestinal tract
- Gastroesophageal reflux disease
- Irritable bowel syndrome
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