Zinc finger protein 107
Zinc finger protein 107 (ZNF107), also known as Zinc finger protein 107 homolog, is a protein that in humans is encoded by the ZNF107 gene. This protein is a member of the zinc finger family of proteins, which are characterized by the presence of zinc finger domains. These domains are known to play a crucial role in DNA binding, RNA binding, and protein-protein interactions.
Structure[edit | edit source]
ZNF107 is a nuclear protein that contains several C2H2-type zinc fingers. The C2H2-type zinc finger is a type of zinc finger domain, which is a common protein structural motif involved in binding DNA, RNA, proteins, and other small molecules. The structure of the zinc finger domain allows it to interact with these molecules, influencing the function of the protein.
Function[edit | edit source]
ZNF107 is believed to act as a transcription factor, regulating the expression of other genes. Transcription factors are proteins that control the rate of transcription of genetic information from DNA to messenger RNA, by binding to a specific DNA sequence. The function of ZNF107 is not fully understood, but it is thought to play a role in cellular processes such as cell growth, cell differentiation, and apoptosis.
Clinical significance[edit | edit source]
While the exact role of ZNF107 in human disease is not fully understood, alterations in the expression or function of this protein have been associated with several types of cancer, including breast cancer, prostate cancer, and lung cancer. Further research is needed to fully understand the role of ZNF107 in these diseases.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD