Zovia 1/35E-28

From WikiMD's Food, Medicine & Wellness Encyclopedia

Zovia 1/35E-28 is a combination oral contraceptive pill used in the prevention of pregnancy. It is part of the broader category of birth control methods that utilize hormonal modulation to prevent ovulation, fertilize implantation, or both. Zovia 1/35E-28 consists of two main active ingredients: ethinyl estradiol, a synthetic form of the female hormone estrogen, and ethynodiol diacetate, a progestin. The combination of these two hormones provides an effective barrier against pregnancy when taken as directed.

Composition and Dosage[edit | edit source]

Zovia 1/35E-28 is typically packaged in a 28-day cycle regimen, where 21 pills contain the active hormones (ethinyl estradiol and ethynodiol diacetate), and the remaining 7 pills are placebo or non-hormonal pills, which are included to maintain the habit of daily intake. The specific dosage of ethinyl estradiol is 35 micrograms, and ethynodiol diacetate varies depending on the formulation.

Mechanism of Action[edit | edit source]

The primary mechanism by which Zovia 1/35E-28 prevents pregnancy is by inhibiting ovulation, the release of an egg from the ovaries. Ethinyl estradiol and ethynodiol diacetate work synergistically to suppress the pituitary gland's release of the follicle-stimulating hormone (FSH) and luteinizing hormone (LH), which are necessary for ovulation. Additionally, this contraceptive alters the cervical mucus, making it more difficult for sperm to enter the uterus, and changes the lining of the uterus, reducing the likelihood of implantation should fertilization occur.

Indications[edit | edit source]

Zovia 1/35E-28 is primarily indicated for the prevention of pregnancy. However, like many combination oral contraceptives, it may also be prescribed for the management of menstrual disorders, such as heavy or irregular menstrual bleeding, dysmenorrhea (painful menstruation), and to reduce the risk of ovarian cysts. Additionally, it may be used in the treatment of acne in women seeking an oral contraceptive for birth control.

Side Effects[edit | edit source]

Common side effects associated with Zovia 1/35E-28 include, but are not limited to, nausea, vomiting, headache, bloating, breast tenderness, and mood changes. More serious side effects may include an increased risk of blood clots, stroke, and heart attack, especially in women who smoke and are over the age of 35.

Contraindications[edit | edit source]

Zovia 1/35E-28 should not be used by individuals with a history of thrombotic disorders, uncontrolled hypertension, breast cancer, or those who are pregnant. It is also contraindicated in individuals with a known hypersensitivity to any of the components of the medication.

Interactions[edit | edit source]

Certain medications and supplements may interact with Zovia 1/35E-28, affecting its efficacy or increasing the risk of adverse effects. These include, but are not limited to, drugs that induce liver enzymes (such as some anticonvulsants and antibiotics), and herbal supplements like St. John's Wort.

Conclusion[edit | edit source]

Zovia 1/35E-28 is a combination oral contraceptive that offers an effective means of preventing pregnancy when used as directed. It is important for individuals considering Zovia 1/35E-28 to consult with a healthcare provider to ensure it is appropriate for their health status and to discuss potential side effects and interactions with other medications.

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Contributors: Prab R. Tumpati, MD