Α-Methyltryptamine

Α-Methyltryptamine (AMT) is a psychedelic and stimulant of the tryptamine class. It was originally developed as an antidepressant by workers at the Upjohn company in the 1960s.

History

AMT was first synthesized by the Upjohn company in the 1960s as a potential antidepressant, but was found to have psychoactive effects. It was used recreationally in the 1960s and 1970s, and has seen a resurgence in use since the 1990s.

Pharmacology

AMT is a monoamine releaser and a monoamine oxidase inhibitor (MAOI). It acts as a releasing agent of serotonin, norepinephrine, and dopamine. It also acts as a non-selective serotonin receptor agonist.

Effects

The effects of AMT can vary greatly depending on the dose, set, and setting. It can produce effects similar to those of both classical psychedelics and stimulants. These effects include euphoria, visual hallucinations, and increased energy.

Legal status

AMT is a Schedule I controlled substance in the United States, and is also controlled in many other countries. It is often sold on the black market and on the darknet.

See also

• Tryptamine
• Psychedelic drug
• Stimulant
• Upjohn