Α-Pyrrolidinobutiophenone

From WikiMD.com - Food, Medicine & Wellness Encyclopedia

Synthetic stimulant of the cathinone class


Α-Pyrrolidinobutiophenone
INN
Drug class
Routes of administration
Pregnancy category
Bioavailability
Metabolism
Elimination half-life
Excretion
Legal status
CAS Number
PubChem
DrugBank
ChemSpider
KEGG


α-Pyrrolidinobutiophenone (also known as α-PBP) is a synthetic stimulant of the cathinone class that has been sold online as a designer drug. It is chemically related to α-Pyrrolidinopentiophenone (α-PVP) and is known for its stimulant effects.

Chemical structure and properties[edit | edit source]

Chemical structure of α-PBP

α-PBP is a derivative of cathinone, which is a naturally occurring stimulant found in the khat plant. The chemical structure of α-PBP includes a pyrrolidine ring, which is a common feature in many synthetic cathinones. This structural feature is believed to contribute to its stimulant properties by affecting the reuptake of neurotransmitters such as dopamine and norepinephrine.

Pharmacology[edit | edit source]

α-PBP acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), which means it increases the levels of these neurotransmitters in the brain by preventing their reabsorption into neurons. This action is similar to that of other stimulants, such as amphetamines and cocaine, and is responsible for the drug's stimulating effects.

Effects and use[edit | edit source]

The effects of α-PBP are similar to those of other stimulants and may include increased alertness, euphoria, and enhanced physical and mental performance. However, these effects are often accompanied by undesirable side effects such as anxiety, paranoia, and increased heart rate. Due to its potency and potential for abuse, α-PBP is considered a substance of concern in many countries.

Legal status[edit | edit source]

The legal status of α-PBP varies by country. In some jurisdictions, it is classified as a controlled substance, making its production, distribution, and possession illegal. In others, it may be regulated under analog laws that control substances similar to those already banned.

Health risks[edit | edit source]

Molecular structure of α-PBP

The use of α-PBP carries significant health risks, particularly when used in high doses or in combination with other substances. Potential adverse effects include cardiovascular problems, neurological issues, and psychological disturbances. Long-term use can lead to addiction and other serious health complications.

Related pages[edit | edit source]

WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD