1,2,4-Butanetriol

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1,2,4-Butanetriol is a clear, colorless, viscous organic compound that is classified as a polyol (a type of alcohol). It has the chemical formula C4H10O3 and is primarily used in the production of plastics, resins, and explosives.

Structure and Properties[edit | edit source]

1,2,4-Butanetriol has a linear structure with three hydroxyl groups (-OH) attached to the carbon atoms. The presence of these hydroxyl groups makes the compound highly hydrophilic, meaning it readily absorbs water from the environment. It has a boiling point of 230°C and a melting point of 49°C.

Production[edit | edit source]

1,2,4-Butanetriol is typically produced through the hydrogenation of malonic acid or its ester derivatives. This process involves the addition of hydrogen atoms to the malonic acid molecule, which reduces it to 1,2,4-butanetriol.

Applications[edit | edit source]

Due to its unique properties, 1,2,4-Butanetriol is used in a variety of industrial applications. It is a key ingredient in the production of certain types of plastics and resins, where it acts as a plasticizer to increase flexibility and durability. It is also used in the manufacture of explosives, specifically as a precursor to the production of butanetriol trinitrate, a powerful explosive.

In addition, 1,2,4-Butanetriol has potential applications in the field of medicine. It has been studied as a potential treatment for cystic fibrosis, as it can help to increase the hydration of mucus in the lungs, making it easier to clear.

Safety and Environmental Impact[edit | edit source]

Like many organic compounds, 1,2,4-Butanetriol can be harmful if ingested or if it comes into contact with the skin or eyes. It is also potentially harmful if inhaled. Therefore, it is important to handle this compound with care and to use appropriate personal protective equipment.

In terms of environmental impact, 1,2,4-Butanetriol is biodegradable and is not considered to be a significant environmental hazard. However, like all chemicals, it should be disposed of responsibly to minimize any potential harm to the environment.

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Contributors: Prab R. Tumpati, MD