From WikiMD's Food, Medicine & Wellness Encyclopedia

1,3-Propanediol (also known as 1,3-PDO) is a organic diol that is commonly used in the polymer industry. It is a colorless, viscous liquid that is miscible with water.

Structure and properties[edit | edit source]

1,3-Propanediol has the chemical formula C3H8O2. It consists of a three-carbon chain with hydroxyl groups at the first and third carbon atoms. The molecule is chiral, meaning it has a non-superimposable mirror image. However, the compound is usually encountered as a racemic mixture, which is optically inactive.

Production[edit | edit source]

1,3-Propanediol can be produced through several methods. One common method is the hydroformylation of ethylene oxide to form a mixture of 1,3- and 1,2-propanediol. Another method is the biological production of 1,3-propanediol using certain strains of E. coli or Clostridium bacteria.

Uses[edit | edit source]

1,3-Propanediol is primarily used in the production of polyesters, polyurethanes, and polyethers. It is also used as a solvent in the pharmaceutical industry and as an antifreeze in the automotive industry.

Safety[edit | edit source]

1,3-Propanediol is generally considered safe for use. However, it can cause irritation to the eyes, skin, and respiratory tract. Ingestion can lead to gastrointestinal upset.

See also[edit | edit source]

References[edit | edit source]


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Contributors: Prab R. Tumpati, MD