1-Fluoronaphthalene

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1-Fluoronaphthalene is a fluorinated hydrocarbon that belongs to the class of organic compounds known as naphthalenes. It is a colorless liquid with a characteristic aromatic odor and is primarily used in organic synthesis.

Chemical Properties[edit | edit source]

1-Fluoronaphthalene has the chemical formula C10H7F, and its molecular weight is 146.16 g/mol. It has a boiling point of 59-60 °C at 12 mmHg and a melting point of -16 °C. The compound is insoluble in water but soluble in most organic solvents such as ethanol, acetone, and diethyl ether.

Synthesis[edit | edit source]

The synthesis of 1-fluoronaphthalene involves the electrophilic aromatic substitution of naphthalene with fluorine. This reaction is typically carried out in the presence of a catalyst such as antimony pentafluoride or hydrogen fluoride.

Applications[edit | edit source]

1-Fluoronaphthalene is primarily used as a building block in organic synthesis. It is used in the synthesis of various fluorinated compounds, including pharmaceuticals and agrochemicals. It is also used as a fluorinating agent in the production of fluoropolymers.

Safety[edit | edit source]

Like many organic solvents, 1-fluoronaphthalene is flammable and should be handled with care. It can cause skin and eye irritation, and prolonged exposure can lead to respiratory problems. It is recommended to use appropriate personal protective equipment when handling this compound.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD