2,3-Methylenedioxyamphetamine

2,3-Methylenedioxyamphetamine (2,3-MDA) is a chemical compound that belongs to the class of amphetamines. It is a structural isomer of the more well-known 3,4-methylenedioxyamphetamine (3,4-MDA), which is a psychoactive drug. The 2,3-MDA isomer is less studied and is not known to have significant psychoactive effects.

Chemical Structure

2,3-Methylenedioxyamphetamine is characterized by the presence of a methylenedioxy group attached to the 2 and 3 positions of the phenyl ring of the amphetamine backbone. This structural configuration differentiates it from its isomer, 3,4-MDA, where the methylenedioxy group is attached to the 3 and 4 positions.

Synthesis

The synthesis of 2,3-MDA involves the formation of the methylenedioxy bridge on the phenyl ring of the amphetamine structure. This can be achieved through various chemical reactions, typically involving the use of reagents that facilitate the formation of the methylenedioxy linkage.

Pharmacology

The pharmacological properties of 2,3-MDA are not well-documented. Unlike its isomer 3,4-MDA, which is known for its psychoactive properties, 2,3-MDA does not appear to have significant effects on the central nervous system. Its interaction with neurotransmitter systems, such as serotonin, dopamine, and norepinephrine, has not been extensively studied.

Legal Status

Due to its structural similarity to other controlled substances, 2,3-MDA may be subject to regulation under various national and international drug control laws. However, its specific legal status can vary by jurisdiction.

Related Compounds

2,3-MDA is part of a broader class of compounds known as substituted amphetamines. Other related compounds include:

• 3,4-Methylenedioxyamphetamine (3,4-MDA)
• 3,4-Methylenedioxymethamphetamine (MDMA)
• Amphetamine

Related Pages

• Amphetamine
• Psychoactive drug
• Substituted amphetamines