2,5-Dimethoxy-4-sec-butylamphetamine
Psychedelic drug of the phenethylamine class
2,5-Dimethoxy-4-sec-butylamphetamine (DOSB) is a psychedelic drug belonging to the phenethylamine class. It is a structural analog of 2,5-dimethoxy-4-bromoamphetamine (DOB) and is known for its psychoactive effects.
Chemical Structure[edit | edit source]
DOSB is a substituted amphetamine, characterized by the presence of methoxy groups at the 2 and 5 positions of the phenyl ring and a sec-butyl group at the 4 position. This structural configuration is responsible for its psychoactive properties.
Pharmacology[edit | edit source]
DOSB acts primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor, which is believed to be the primary mechanism underlying its psychedelic effects. The compound's interaction with serotonin receptors leads to alterations in perception, mood, and cognition.
Effects[edit | edit source]
The effects of DOSB are similar to those of other psychedelic phenethylamines, such as 2,5-dimethoxy-4-iodoamphetamine (DOI) and 2,5-dimethoxy-4-methylamphetamine (DOM). Users report visual and auditory hallucinations, altered thought processes, and changes in time perception. The intensity and duration of these effects can vary based on dosage and individual sensitivity.
Synthesis[edit | edit source]
The synthesis of DOSB involves the alkylation of 2,5-dimethoxyphenethylamine with sec-butyl halides. This process requires careful control of reaction conditions to ensure the correct substitution pattern on the phenyl ring.
Legal Status[edit | edit source]
The legal status of DOSB varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated psychedelics. Users should be aware of the legal implications of possessing or distributing DOSB in their region.
Related Compounds[edit | edit source]
DOSB is part of a family of compounds known as the "DOx" series, which includes other psychedelics such as DOI, DOB, and DOM. These compounds share a common phenethylamine backbone with various substitutions that influence their pharmacological profiles and effects.
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