From WikiMD's Food, Medicine & Wellness Encyclopedia

2-Hydroxy-3-methoxybenzaldehyde is an organic compound with the chemical formula C8H8O3. It is a derivative of benzaldehyde, characterized by the presence of a hydroxyl group and a methoxy group on the benzene ring.

Structure and Properties[edit | edit source]

2-Hydroxy-3-methoxybenzaldehyde is a white crystalline solid at room temperature. It has a molar mass of 152.15 g/mol. The compound is soluble in water, ethanol, and diethyl ether.

The structure of 2-Hydroxy-3-methoxybenzaldehyde consists of a benzene ring, which is a cyclic aromatic compound with alternating double and single bonds. Attached to this ring are a hydroxyl group (-OH) at the 2-position and a methoxy group (-OCH3) at the 3-position. The presence of these functional groups gives the compound its unique chemical properties.

Synthesis[edit | edit source]

2-Hydroxy-3-methoxybenzaldehyde can be synthesized through the Friedel-Crafts alkylation of benzaldehyde with dimethyl sulfate in the presence of aluminium chloride as a catalyst. The resulting product is then hydrolyzed to yield 2-Hydroxy-3-methoxybenzaldehyde.

Applications[edit | edit source]

2-Hydroxy-3-methoxybenzaldehyde is used in the synthesis of various pharmaceuticals and dyes. It is also used as a flavoring agent in the food industry due to its pleasant, sweet aroma.

Safety[edit | edit source]

Like many organic compounds, 2-Hydroxy-3-methoxybenzaldehyde should be handled with care. It can cause irritation to the skin and eyes, and may be harmful if swallowed or inhaled.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD