25B-NBOH

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25B-NBOH[edit | edit source]

Chemical structure of 25B-NBOH

25B-NBOH is a synthetic psychedelic compound that belongs to the NBOH class of drugs. It is a derivative of the phenethylamine 2C-B, and is known for its potent serotonin receptor agonist activity, particularly at the 5-HT2A receptor.

Chemical Structure[edit | edit source]

25B-NBOH is chemically known as 2-(4-bromo-2,5-dimethoxyphenyl)-N-[(2-hydroxyphenyl)methyl]ethanamine. It features a bromine atom at the 4-position of the phenyl ring, which is a characteristic feature of the 2C-B family of compounds. The NBOH series is distinguished by the presence of a 2-hydroxybenzyl group attached to the nitrogen atom.

Pharmacology[edit | edit source]

25B-NBOH acts primarily as a potent agonist at the 5-HT2A receptor, which is the primary target for most psychedelic drugs. This receptor is a subtype of the serotonin receptor family and is involved in the modulation of mood, perception, and cognition. The activation of 5-HT2A receptors by 25B-NBOH is responsible for its psychedelic effects.

Effects[edit | edit source]

The effects of 25B-NBOH are similar to those of other psychedelics, such as LSD and psilocybin. Users report altered sensory perception, changes in mood, and visual hallucinations. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status[edit | edit source]

The legal status of 25B-NBOH varies by country. In some jurisdictions, it is classified as a controlled substance due to its structural similarity to other banned psychedelics. In others, it may be unscheduled but subject to analogue laws that prohibit substances similar to controlled drugs.

Safety and Toxicity[edit | edit source]

There is limited research on the safety and toxicity of 25B-NBOH. As with other research chemicals, the long-term effects are not well understood, and caution is advised when handling or using this compound.

Related Compounds[edit | edit source]

See Also[edit | edit source]

Related Pages[edit | edit source]

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Contributors: Prab R. Tumpati, MD