2CE-5iPrO

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A psychedelic phenethylamine


2CE-5iPrO is a synthetic psychedelic compound belonging to the phenethylamine class. It is a derivative of the 2C family of drugs, which are known for their psychoactive properties. The compound is characterized by the presence of an isopropoxy group at the 5-position of the phenethylamine backbone.

Chemical structure of 2CE-5iPrO

Chemical Structure and Properties[edit | edit source]

2CE-5iPrO is chemically known as 2-(4-ethoxy-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine. The compound features a phenethylamine core with various substitutions that contribute to its unique pharmacological profile. The presence of the isopropoxy group at the 5-position is a distinguishing feature that influences its interaction with serotonin receptors.

Pharmacology[edit | edit source]

2CE-5iPrO is believed to act primarily as a serotonin receptor agonist, similar to other compounds in the 2C family. It is thought to bind to the 5-HT2A receptor, which is associated with the psychedelic effects experienced by users. The compound's exact mechanism of action and its affinity for other receptor subtypes remain subjects of research.

Effects[edit | edit source]

The effects of 2CE-5iPrO are reported to be similar to those of other 2C compounds, characterized by alterations in perception, mood, and cognition. Users may experience visual and auditory hallucinations, changes in thought patterns, and an altered sense of time. The intensity and duration of these effects can vary based on dosage and individual sensitivity.

Safety and Toxicity[edit | edit source]

As with many research chemicals, the safety profile of 2CE-5iPrO is not well-established. There is limited data on its toxicity, potential for abuse, and long-term effects. Users are advised to exercise caution and adhere to harm reduction practices when experimenting with this compound.

Legal Status[edit | edit source]

The legal status of 2CE-5iPrO varies by country. In some jurisdictions, it may be classified as a controlled substance due to its structural similarity to other regulated phenethylamines. Researchers and users should be aware of the legal implications of possessing or distributing this compound.

Related Compounds[edit | edit source]

2CE-5iPrO is part of a broader class of phenethylamines that includes other notable compounds such as 2C-B, 2C-I, and 2C-E. These compounds share a common structural framework but differ in their specific substitutions, leading to variations in their pharmacological effects.

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Contributors: Prab R. Tumpati, MD