3-Chloropropionitrile

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3-Chloropropionitrile.svg


3-Chloropropionitrile is an organic compound with the chemical formula C_3H_4ClN. It is a colorless liquid that is used as an intermediate in the synthesis of various chemicals, including pharmaceuticals and agrochemicals.

Chemical Properties[edit | edit source]

3-Chloropropionitrile is a nitrile compound, characterized by the presence of a cyano group (-C≡N) attached to a propyl chain with a chlorine atom on the third carbon. It has a molecular weight of 89.52 g/mol and a density of 1.08 g/cm³. The compound has a melting point of -87 °C and a boiling point of 142 °C.

Synthesis[edit | edit source]

3-Chloropropionitrile can be synthesized through various methods, including the reaction of acrylonitrile with hydrogen chloride in the presence of a catalyst. Another method involves the chlorination of propionitrile.

Applications[edit | edit source]

3-Chloropropionitrile is primarily used as an intermediate in the production of other chemicals. It is utilized in the synthesis of pharmaceuticals, where it serves as a building block for more complex molecules. Additionally, it is used in the manufacture of agrochemicals, which are chemicals used in agriculture to protect crops and enhance growth.

Safety and Handling[edit | edit source]

3-Chloropropionitrile is classified as a hazardous substance. It is important to handle it with care, using appropriate personal protective equipment (PPE) such as gloves and goggles. The compound should be stored in a cool, dry place, away from sources of ignition. In case of contact with skin or eyes, it is advised to rinse immediately with plenty of water and seek medical attention.

See Also[edit | edit source]

References[edit | edit source]

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Contributors: Prab R. Tumpati, MD