4'-Methyl-α-pyrrolidinobutiophenone

From WikiMD's Wellness Encyclopedia

4'-Methyl-α-pyrrolidinobutiophenone (MPBP) is a stimulant compound which has been reported as a novel designer drug. It is closely related to pyrovalerone, being simply its chain-lengthened homologue. In the pyrrolidinophenone series, stimulant activity is maintained so long as the positions of the aromatic ring, carbonyl group, and amino group are held constant, while the alkyl chain is varied.

Chemistry[edit | edit source]

4'-Methyl-α-pyrrolidinobutiophenone is a synthetic cathinone. Cathinones are structurally similar to amphetamines, they contain a phenethylamine core featuring a phenyl ring bound to an amino (NH2) group through an ethyl chain with an additional methyl substitution at Rα. Cathinones such as MPBP are alpha-methylated phenethylamines (i.e., amphetamines) but differ from them with the addition of a keto functional group, a carbonyl group at Rβ.

Pharmacology[edit | edit source]

The pharmacology of 4'-Methyl-α-pyrrolidinobutiophenone is largely unknown. As a cathinone, it is likely to act as a norepinephrine-dopamine reuptake inhibitor (NDRI), but its action may also involve suppression of vesicular monoamine transporter 2 (VMAT2), leading to increased concentrations of synaptic neurotransmitters, particularly dopamine and norepinephrine.

Legality[edit | edit source]

The legal status of 4'-Methyl-α-pyrrolidinobutiophenone varies by country, but it is often considered a controlled substance due to its potential for abuse and addiction. In many jurisdictions, it is illegal to manufacture, distribute, or possess this substance.

See also[edit | edit source]

Medicine-stub.png
This article is a stub related to medicine. You can help WikiMD by expanding it!


WikiMD
Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD

Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD

WikiMD's Wellness Encyclopedia

Let Food Be Thy Medicine
Medicine Thy Food - Hippocrates

Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.

Contributors: Prab R. Tumpati, MD