4-HO-EPT

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4-HO-EPT

Chemical structure of 4-HO-EPT
3D model of 4-HO-EPT

4-HO-EPT (4-Hydroxy-N-ethyl-N-propyltryptamine) is a psychedelic compound belonging to the tryptamine class. It is structurally related to psilocin, the active component in psilocybin mushrooms.

Chemical Structure[edit | edit source]

4-HO-EPT is a tryptamine derivative, characterized by a hydroxy group at the fourth position of the indole ring and an ethyl and propyl group attached to the nitrogen atom. This structure is similar to other 4-hydroxytryptamines, such as 4-HO-DMT and 4-HO-MET.

Pharmacology[edit | edit source]

As a psychedelic, 4-HO-EPT is believed to act primarily as a serotonin receptor agonist, particularly at the 5-HT2A receptor. This action is thought to be responsible for its psychoactive effects, which can include alterations in perception, mood, and cognition.

Effects[edit | edit source]

The effects of 4-HO-EPT are similar to those of other psychedelic tryptamines. Users report visual and auditory hallucinations, changes in thought patterns, and an altered sense of time. The intensity and duration of these effects can vary depending on the dose and individual sensitivity.

Legal Status[edit | edit source]

The legal status of 4-HO-EPT varies by country. In some jurisdictions, it may be classified as a controlled substance, while in others it may be unscheduled. Users should be aware of the legal implications of possessing or using this compound in their region.

Safety and Toxicity[edit | edit source]

There is limited data on the safety and toxicity of 4-HO-EPT. As with other psychedelics, it is important to approach its use with caution, considering factors such as set, setting, and personal health. Potential risks include psychological distress and the exacerbation of pre-existing mental health conditions.

Related Compounds[edit | edit source]

See Also[edit | edit source]

Gallery[edit | edit source]

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Contributors: Prab R. Tumpati, MD