4-Methyl-αMT

From WikiMD's Food, Medicine & Wellness Encyclopedia

4-Methyl-αMT (also known as 4-Methyl-alpha-methyltryptamine) is a psychedelic and hallucinogenic drug that is structurally related to alpha-Methyltryptamine (αMT) and tryptamine itself. It is classified as a serotonin receptor agonist and monoamine oxidase inhibitor (MAOI).

History[edit | edit source]

4-Methyl-αMT was first synthesized in the 1960s, but its psychoactive effects were not widely recognized until the 1990s. It was initially used in scientific research before gaining popularity as a recreational drug.

Pharmacology[edit | edit source]

As a serotonin receptor agonist, 4-Methyl-αMT stimulates the release of serotonin, a neurotransmitter that plays a key role in mood regulation. It also inhibits the action of monoamine oxidase, an enzyme that breaks down serotonin and other monoamines. This dual action can lead to an excess of serotonin in the brain, which can result in a range of psychoactive effects.

Effects[edit | edit source]

The effects of 4-Methyl-αMT can vary widely depending on the dose, the individual's physiology, and the context in which the drug is used. Common effects include visual and auditory hallucinations, altered perception of time, and heightened emotional sensitivity. At higher doses, the drug can cause confusion, agitation, and potentially dangerous increases in heart rate and blood pressure.

Legal Status[edit | edit source]

The legal status of 4-Methyl-αMT varies by country. In some jurisdictions, it is classified as a controlled substance and its possession, sale, and use are subject to legal penalties.

Health Risks[edit | edit source]

As with other psychedelic drugs, the use of 4-Methyl-αMT carries potential health risks. These include psychological distress, dangerous increases in heart rate and blood pressure, and the risk of serotonin syndrome, a potentially life-threatening condition caused by an excess of serotonin in the brain.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD