4-Methyl-α-methyltryptamine

4-Methyl-α-methyltryptamine (also known as 4-MMT or 4-MAMT) is a psychedelic drug and a substituted tryptamine. It is structurally related to tryptamine and other hallucinogenic substances.

Chemistry

4-Methyl-α-methyltryptamine is a synthetic compound of the tryptamine class. Tryptamines share a core structure comprised of a bicylic indole heterocycle attached at R3 to an amino group via an ethyl side chain. 4-MMT is substituted at R4 of its indole heterocycle with a methyl group. It also contains a methyl group bound to the terminal amine RN of its tryptamine backbone (α-methyltryptamine).

Pharmacology

The pharmacology of 4-MMT is not well-studied. However, it is known to act as a serotonin receptor agonist. The drug's effects are believed to come from its efficacy at the 5-HT2A receptor. However, the role of these interactions and how they result in the psychedelic experience continues to remain elusive.

Effects

The effects of 4-MMT can vary greatly, depending on the dose and individual's physiology. Common effects include visual hallucinations, changes in perception, euphoria, and cognitive enhancement. At higher doses, it can cause nausea, anxiety, and increased heart rate.

Legal Status

The legal status of 4-MMT varies by country. In some countries, it is a controlled substance, while in others it is legal to possess for personal use.

See Also

• Tryptamine
• Psychedelic drug
• Serotonin receptor