6-acetyl-2,3,4,5-tetrahydropyridine

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6-Acetyl-2,3,4,5-tetrahydropyridine (A-THP) is a chemical compound that belongs to the class of organic compounds known as pyridines and derivatives. These are compounds containing a pyridine ring, which is a six-membered aromatic heterocycle with one nitrogen atom and five carbon atoms.

Chemical Structure[edit | edit source]

Chemical structure of 6-Acetyl-2,3,4,5-tetrahydropyridine

The chemical structure of 6-Acetyl-2,3,4,5-tetrahydropyridine consists of a pyridine ring, which is a six-membered aromatic heterocycle with one nitrogen atom and five carbon atoms. The pyridine ring is substituted at the 6-position by an acetyl group.

Properties[edit | edit source]

6-Acetyl-2,3,4,5-tetrahydropyridine is a hydrophobic compound due to the presence of the acetyl group. It is soluble in organic solvents such as ethanol, methanol, and chloroform.

Synthesis[edit | edit source]

The synthesis of 6-Acetyl-2,3,4,5-tetrahydropyridine involves the acetylation of 2,3,4,5-tetrahydropyridine using acetic anhydride in the presence of a catalyst such as sulfuric acid.

Applications[edit | edit source]

6-Acetyl-2,3,4,5-tetrahydropyridine is used in the synthesis of various pharmaceutical compounds. It is also used as a reagent in organic synthesis.

Safety[edit | edit source]

As with all chemicals, 6-Acetyl-2,3,4,5-tetrahydropyridine should be handled with care. It should be stored in a cool, dry place, away from heat and open flames.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD