8,11-Dihydroxytetrahydrocannabinol

8,11-Dihydroxytetrahydrocannabinol (also known as 8,11-DiOH-THC) is a metabolite of tetrahydrocannabinol (THC), the primary psychoactive compound found in cannabis. It is produced in the body after consumption of THC and has been studied for its potential therapeutic effects.

Chemistry

8,11-Dihydroxytetrahydrocannabinol is a hydroxylated metabolite of THC, meaning it has additional hydroxyl groups attached to its molecular structure. This modification occurs in the body's metabolism of THC, specifically in the liver, where enzymes such as cytochrome P450 facilitate the addition of these hydroxyl groups.

Pharmacology

The pharmacological effects of 8,11-Dihydroxytetrahydrocannabinol are not fully understood. However, it is known to interact with the endocannabinoid system, a complex cell-signaling system in the body that plays a role in regulating a wide range of functions and processes. This system includes two main types of receptors, cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2), which are found in various parts of the body and are known to be activated by THC and its metabolites.

Potential Therapeutic Uses

Research into the potential therapeutic uses of 8,11-Dihydroxytetrahydrocannabinol is ongoing. Some studies suggest that it may have anti-inflammatory and analgesic effects, making it a potential candidate for the treatment of conditions such as chronic pain and inflammatory diseases. However, more research is needed to fully understand its effects and potential medical applications.

See Also

• Cannabinoid
• Cannabis (drug)
• Endocannabinoid system
• Tetrahydrocannabinol

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