8-Cyclopentyl-1,3-dimethylxanthine

8-Cyclopentyl-1,3-dimethylxanthine (also known as 8-CPT or 8-Cyclopentyltheophylline) is a potent and selective adenosine receptor antagonist, primarily used in the research of the adenosine system. It is a derivative of xanthine.

Chemistry

8-Cyclopentyl-1,3-dimethylxanthine is a xanthine derivative. Xanthine is a purine base found in most human body tissues and fluids and in other organisms. The compound is a white crystalline substance that forms salts with acids and bases.

Pharmacology

8-Cyclopentyl-1,3-dimethylxanthine acts as an antagonist at the adenosine A1 receptor and adenosine A2A receptor, but has weak activity at the adenosine A2B receptor and adenosine A3 receptor. This selectivity makes it a useful tool in the study of the adenosine system.

Medical Use

While 8-Cyclopentyl-1,3-dimethylxanthine is primarily used in research, it has potential therapeutic applications. It has been suggested that antagonists of the adenosine A1 receptor may be useful in the treatment of cardiac arrhythmias, asthma, and certain types of pain. However, further research is needed to confirm these possibilities.

See Also

• Adenosine receptor
• Xanthine

References

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