ALPPL2

ALPPL2 (also known as Alkaline Phosphatase, Placental Like 2) is a protein that in humans is encoded by the ALPPL2 gene. It is a member of the alkaline phosphatase family of proteins, which are involved in a variety of biological processes, including bone mineralization, lipid metabolism, and embryonic development.

Function

The ALPPL2 protein is a glycoprotein that is anchored to the cell membrane. It is thought to play a role in the metabolism of phosphate and calcium, two essential minerals for the proper functioning of the body. The exact function of ALPPL2 is not fully understood, but it is believed to be involved in the regulation of cell growth and cell differentiation.

Clinical significance

Mutations in the ALPPL2 gene have been associated with several medical conditions. For example, elevated levels of ALPPL2 have been found in patients with ovarian cancer, suggesting that it may play a role in the development of this disease. Additionally, ALPPL2 has been implicated in gestational diabetes, a condition that affects pregnant women.

Research

Research into the function and clinical significance of ALPPL2 is ongoing. Understanding the role of this protein in the body could lead to new treatments for diseases such as ovarian cancer and gestational diabetes.

See also

• Alkaline phosphatase
• Gene
• Protein
• Ovarian cancer
• Gestational diabetes

References

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