Alkaline phosphatase

Other names / abbreviations[edit | edit source]

Abbreviated as Alk Phos, Alk P, alkaline phospatase is an enzyme normally present in certain cells within the liver, bone, kidney, intestine, and placenta.

How it is released?[edit | edit source]

When the cells are destroyed in those tissues, more of the enzyme leaks into the blood, and levels rise in proportion to the severity of the condition.

Clinical utility[edit | edit source]

Measurement of this enzyme is used as an indication of the health of the liver.

Normal levels[edit | edit source]

Normal range: 20-90 I.U./liter. Normal range may vary somewhat according to the brand of laboratory assay materials used.

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v t e Clinical biochemistry blood tests (CPT 82000–84999)
Electrolytes	Sodium Potassium Chloride Calcium Renal function Creatinine Urea BUN-to-creatinine ratio Plasma osmolality Serum osmolal gap
Acid-base	Anion gap Arterial blood gas Base excess Bicarbonate CO₂ content
Iron tests	Ferritin Serum iron Transferrin saturation Total iron-binding capacity Transferrin Transferrin receptor
Hormones	ACTH stimulation test Thyroid function tests Thyroid-stimulating hormone
Metabolism	Blood lipids
Cardiovascular	Cardiac marker Troponin test CPK-MB test Lactate dehydrogenase Myoglobin Glycogen phosphorylase isoenzyme BB
Liver function tests	Proteins Human serum albumin Serum total protein ALP transaminases ALT AST AST/ALT ratio Bilirubin Unconjugated Conjugated
Pancreas	Amylase Lipase Pancreatic lipase

v t e Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)