Phosphate group

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Phosphate Group

A phosphate group is a functional group or radical comprised of phosphorus attached to four oxygen, and with a net negative charge, thus represented as PO43−. The phosphate group is the conjugate base of the hydrogen phosphate ion HPO42−, which in turn is the conjugate base of the dihydrogen phosphate ion H2PO4, which in turn is the conjugate base of orthophosphoric acid, H3PO4.

Chemical Properties[edit | edit source]

Phosphate groups have strong polar characteristics, which allow them to participate in a variety of chemical reactions. They are commonly found in organic and inorganic compounds, such as DNA and RNA, where they connect the nucleotides to form the nucleic acid structure.

Biological Role[edit | edit source]

In biological systems, phosphate groups are vital for energy storage and transfer. They are a key component of ATP, the primary energy currency of cells. Phosphate groups are also crucial in the regulation of metabolic pathways, through processes such as phosphorylation and dephosphorylation.

Environmental Impact[edit | edit source]

Phosphate groups are also important in environmental contexts, particularly in relation to eutrophication of water bodies. Excessive amounts of phosphate can lead to algal blooms, which can have detrimental effects on water quality and aquatic life.

See Also[edit | edit source]

Phosphate group Resources
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Contributors: Prab R. Tumpati, MD