ARID3B
ARID3B is a protein that in humans is encoded by the ARID3B gene. This protein is a member of the ARID (AT-rich interaction domain) family of proteins. The ARID domain is a highly conserved protein domain that is found in a wide range of organisms.
Function[edit | edit source]
The ARID3B protein is a transcription factor that plays a crucial role in cell differentiation and development. It is particularly important in the development of the nervous system and the heart. Mutations in the ARID3B gene can lead to developmental abnormalities and diseases.
Clinical significance[edit | edit source]
Mutations in the ARID3B gene have been associated with a range of medical conditions. These include intellectual disability, autism, and congenital heart defects. In addition, ARID3B has been implicated in several types of cancer, including breast cancer and leukemia.
Research[edit | edit source]
Research into the ARID3B gene and its associated protein is ongoing. This research is aimed at better understanding the role of ARID3B in development and disease, and at developing potential treatments for conditions associated with mutations in the ARID3B gene.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
