Abelin reaction

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Abelin Reaction is a chemical reaction named after the Swedish chemist John Abelin, who first described it in 1922. It is a type of organic reaction that involves the conversion of an aldehyde or ketone into an alkene in the presence of a base and a halogen.

Mechanism[edit | edit source]

The Abelin Reaction proceeds via a E2 elimination mechanism. The base abstracts a proton from the carbon adjacent to the carbonyl group, forming a carbanion. This carbanion then expels the halogen as a leaving group, forming the alkene.

Applications[edit | edit source]

The Abelin Reaction has been used in the synthesis of various organic compounds, including natural products and pharmaceuticals. It is particularly useful for the synthesis of alkenes from readily available starting materials.

See also[edit | edit source]

References[edit | edit source]

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