Activin and inhibin
Activin and Inhibin are two closely related protein complexes that have almost directly opposite biological effects. Identified in 1986, Activin enhances FSH biosynthesis and secretion, and participates in the regulation of the menstrual cycle. Many other functions have been found to be exerted by activin, including roles in cell proliferation, differentiation, apoptosis, metabolism, homeostasis, immune response, wound repair, and endocrine function. Conversely, inhibin downregulates FSH synthesis and inhibits FSH secretion.
Activin[edit | edit source]
Activin is a protein complex that is involved in a number of important biological functions. It is a dimeric protein composed of two identical or very similar beta subunits. Activin is produced in the gonads, pituitary gland, placenta, and other organs.
Activin has a wide range of biological activities, including stimulation of FSH secretion, regulation of menstrual cycle, cell proliferation, differentiation, wound repair, and immune response. It also plays a role in the regulation of homeostasis and metabolism.
Inhibin[edit | edit source]
Inhibin is a protein complex that inhibits the secretion of follicle-stimulating hormone (FSH). It is a heterodimeric protein composed of an alpha and a beta subunit. The alpha subunit is common to both inhibin and activin, while the beta subunit is distinct.
Inhibin is produced in the gonads (testes in males and ovaries in females) and acts to inhibit the production of FSH by the pituitary gland. In addition to its role in the regulation of the menstrual cycle, inhibin has been implicated in the regulation of reproductive and developmental processes.
Relationship between Activin and Inhibin[edit | edit source]
Activin and inhibin are two closely related proteins that have almost directly opposite biological effects. They are both dimeric proteins that are produced in the gonads and other organs. The main difference between them is that activin stimulates the secretion of FSH, while inhibin inhibits it.
The balance between activin and inhibin is crucial for the regulation of the menstrual cycle and other reproductive processes. Disruptions in this balance can lead to a variety of reproductive disorders.
See also[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD