Alliance for Clinical Trials in Oncology

Alliance for Clinical Trials in Oncology is a leading clinical trial organization that plays a pivotal role in cancer research. It is part of the National Cancer Institute's (NCI) National Clinical Trials Network (NCTN), which is designed to facilitate and streamline cancer research through collaboration and the sharing of resources. The Alliance focuses on conducting clinical trials and research studies that aim to improve the prevention, diagnosis, and treatment of cancer.

History[edit | edit source]

The Alliance for Clinical Trials in Oncology was formed through the merger of three prominent clinical trials organizations: the American College of Surgeons Oncology Group, the Cancer and Leukemia Group B, and the North Central Cancer Treatment Group. This merger was part of a broader NCI initiative to consolidate the clinical trials infrastructure within the United States to enhance efficiency and collaboration among researchers and institutions.

Mission[edit | edit source]

The mission of the Alliance for Clinical Trials in Oncology is to reduce the impact of cancer by conducting high-quality, large-scale, multidisciplinary clinical trials. The organization aims to test the efficacy of new treatments, compare existing therapies, study methods of cancer prevention, and explore methods of cancer screening and diagnosis. Through its work, the Alliance seeks to generate definitive and transformative data that can guide clinical practice and improve outcomes for patients with cancer.

Research and Trials[edit | edit source]

The Alliance conducts research across a wide spectrum of cancers, including but not limited to breast cancer, lung cancer, colorectal cancer, and leukemia. Its clinical trials range from phase I, which tests the safety and dosage of new treatments, to phase III, which compares new treatments with the current standard of care. The organization also engages in translational research, which seeks to move findings from the laboratory into clinical applications as quickly and efficiently as possible.

Membership[edit | edit source]

Membership in the Alliance for Clinical Trials in Oncology includes a diverse group of stakeholders in the cancer research community. This includes, but is not limited to, oncologists, surgeons, radiation therapists, nurses, patient advocates, and researchers from institutions across the United States. Members collaborate on the design, implementation, and analysis of clinical trials, contributing their expertise to advance the field of oncology.

Impact[edit | edit source]

The work of the Alliance for Clinical Trials in Oncology has led to significant advancements in cancer treatment and care. Its clinical trials have contributed to the development of new therapies, the identification of effective treatment combinations, and the establishment of new standards of care. These achievements have not only improved survival rates and quality of life for patients with cancer but have also influenced clinical practice guidelines and policy decisions worldwide.