Allylglycine

Allylglycine is a derivative of the amino acid glycine that has an allyl group replacing one of the hydrogen atoms. It is a convulsant drug that causes seizures by inhibiting the enzyme glutamic acid decarboxylase, thus reducing the production of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA).

Chemistry

Allylglycine is a derivative of the amino acid glycine, where one of the hydrogen atoms is replaced by an allyl group. The allyl group consists of a carbon chain with a double bond, which gives the molecule its unique properties.

Pharmacology

Allylglycine acts as a convulsant drug, causing seizures by inhibiting the enzyme glutamic acid decarboxylase. This enzyme is responsible for the production of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter. By reducing the production of GABA, allylglycine disrupts the balance of excitatory and inhibitory signals in the brain, leading to increased neuronal activity and seizures.

Uses

While allylglycine itself is not used in medicine due to its convulsant effects, it is used in research to study the role of GABA in the brain and the mechanisms of seizures. It is also used to induce seizures in laboratory animals for the study of epilepsy and the development of new anticonvulsant drugs.

See also

• Glycine
• Convulsant
• Glutamic acid decarboxylase
• Gamma-aminobutyric acid

Allylglycine Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.

Translate to: East Asian 中文, 日本, 한국어, South Asian हिन्दी, Urdu, বাংলা, తెలుగు, தமிழ், ಕನ್ನಡ,
Southeast Asian Indonesian, Vietnamese, Thai, မြန်မာဘာသာ, European español, Deutsch, français, русский, português do Brasil, Italian, polski