Alnespirone

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Alnespirone


Alnespirone is a serotonin 5-HT1A receptor agonist. It is classified under the drug class of anxiolytics, which are used to reduce anxiety. Alnespirone has been studied for its potential use in the treatment of Generalized Anxiety Disorder (GAD).

Pharmacology[edit | edit source]

Alnespirone acts as a full agonist at the 5-HT1A receptor, a subtype of the serotonin receptor. This receptor is implicated in a variety of physiological processes, including the regulation of mood and anxiety. By activating this receptor, alnespirone can exert anxiolytic effects.

Clinical Trials[edit | edit source]

Alnespirone has undergone Phase II clinical trials for the treatment of GAD. However, as of now, it has not been approved for use by any regulatory authority.

Side Effects[edit | edit source]

Like other 5-HT1A receptor agonists, alnespirone may cause side effects such as dizziness, nausea, and sleep disturbances. However, these side effects are generally mild and transient.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD