Analgesic nephropathy

From WikiMD's Wellness Encyclopedia

Analgesic nephropathy is a medical condition that results from the long-term use of analgesics, particularly over-the-counter non-prescription drugs, which can lead to chronic kidney disease.

Overview[edit | edit source]

Analgesic nephropathy is a form of nephropathy that is caused by the long-term use of analgesics. The most common analgesics that can cause this condition are non-prescription drugs such as aspirin, paracetamol (also known as acetaminophen), and nonsteroidal anti-inflammatory drugs (NSAIDs).

Causes[edit | edit source]

The main cause of analgesic nephropathy is the prolonged use of analgesics. These drugs can cause damage to the kidneys, leading to chronic kidney disease. The risk of developing this condition increases with the amount and duration of analgesic use.

Symptoms[edit | edit source]

The symptoms of analgesic nephropathy can vary, but they often include back pain, hematuria (blood in the urine), and urinary tract infections. In severe cases, the condition can lead to end-stage renal disease (ESRD), which requires dialysis or a kidney transplant.

Diagnosis[edit | edit source]

Analgesic nephropathy is diagnosed based on a patient's medical history, physical examination, and laboratory tests. The tests may include a urinalysis, blood tests, and imaging studies such as an ultrasound or CT scan of the kidneys.

Treatment[edit | edit source]

The treatment for analgesic nephropathy involves stopping the use of the offending analgesics and managing the symptoms. In severe cases, dialysis or a kidney transplant may be necessary.

Prevention[edit | edit source]

Prevention of analgesic nephropathy involves the judicious use of analgesics. Patients should be educated about the potential risks of long-term analgesic use and should be encouraged to use these drugs only as directed by a healthcare provider.

See also[edit | edit source]

Analgesic nephropathy Resources

Contributors: Prab R. Tumpati, MD