Angioleiomyoma

Angioleiomyoma

Histological image of an angioleiomyoma

An angioleiomyoma is a benign tumor that arises from smooth muscle cells and contains a prominent vascular component. It is a type of leiomyoma, which is a tumor of smooth muscle origin, and is most commonly found in the skin and subcutaneous tissue.

Clinical Presentation

Angioleiomyomas typically present as small, firm, and painful nodules. They are most commonly located in the lower extremities, particularly the legs, but can also occur in other areas of the body. The pain associated with angioleiomyomas is often exacerbated by changes in temperature or pressure.

Pathophysiology

The exact cause of angioleiomyoma formation is not well understood. However, it is believed to arise from the vascular smooth muscle cells. The tumor is characterized by a proliferation of smooth muscle cells surrounding thick-walled blood vessels. The presence of these blood vessels is a distinguishing feature of angioleiomyomas compared to other types of leiomyomas.

Diagnosis

Diagnosis of an angioleiomyoma is typically made through histological examination. A biopsy of the lesion will reveal the characteristic features of smooth muscle cells and prominent blood vessels. The histological image shown here demonstrates these features, with smooth muscle bundles surrounding vascular channels.

Treatment

The primary treatment for angioleiomyoma is surgical excision. Complete removal of the tumor usually results in resolution of symptoms, including pain. Recurrence after excision is rare.

Related Pages

• Leiomyoma
• Benign tumor
• Smooth muscle
• Vascular tumor