Ansoxetine

Ansoxetine

Ansoxetine (also known as MD-354) is a chemical compound that is classified as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI). It was originally developed in the 1970s by the pharmaceutical industry for potential use as an antidepressant, but it was never marketed.

History

Ansoxetine was first synthesized in the 1970s by the pharmaceutical company Merck & Co.. It was initially developed as a potential treatment for depression and other mood disorders. However, despite showing promise in early clinical trials, the drug was never brought to market.

Pharmacology

As a SNDRI, Ansoxetine works by inhibiting the reuptake of the neurotransmitters serotonin, norepinephrine, and dopamine in the brain. This increases the levels of these neurotransmitters in the synaptic cleft, which can help to alleviate symptoms of depression and other mood disorders.

Potential Uses

While Ansoxetine was never marketed as an antidepressant, research into its properties and effects continues. Some studies suggest that it may have potential uses in the treatment of other conditions, such as attention deficit hyperactivity disorder (ADHD) and chronic pain.

Side Effects

Like all drugs, Ansoxetine has the potential to cause side effects. These can include nausea, dizziness, insomnia, and increased heart rate. However, as the drug was never marketed, comprehensive data on its side effects is not available.

See Also

• Serotonin-norepinephrine-dopamine reuptake inhibitor
• Antidepressant
• Neurotransmitter