Arecoline

Arecoline is a alkaloid that is found in the betel nut of the Areca palm. It is a base, with a pKa of 6.8. Arecoline is a muscarinic partial agonist, which can stimulate the muscarinic acetylcholine receptor.

Chemistry

Arecoline is an oily liquid that is colorless to yellowish-brown. It is soluble in water, alcohol, and ether. The chemical formula of arecoline is C8H13NO2, and its molecular weight is 155.19 g/mol. It is a tertiary amine, with a single nitrogen atom bonded to three carbon atoms.

Pharmacology

Arecoline has been found to have several pharmacological effects. It is a muscarinic partial agonist, which means it can stimulate the muscarinic acetylcholine receptor. This can lead to a variety of effects, including increased salivation, sweating, and bronchial secretions, as well as a decrease in heart rate and blood pressure.

Toxicity

Arecoline is toxic and can cause a variety of health problems. It is a known carcinogen, and long-term use can lead to oral cancer. It can also cause a variety of other health problems, including liver damage, heart disease, and neurological problems.

Uses

Arecoline has been used in traditional medicine for a variety of purposes. It has been used as a stimulant, a diuretic, and a remedy for worm infestations. However, due to its toxicity, its use is generally discouraged in modern medicine.

See also

• Areca nut
• Muscarinic acetylcholine receptor
• Alkaloid

Arecoline Resources
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