Livedoid vasculopathy

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(Redirected from Atrophie blanche)

Livedoid vasculopathy (LV), also known as livedoid vasculitis or atrophie blanche, is a rare, chronic vascular disorder characterized by recurrent painful ulcerations and purpuric skin lesions, primarily affecting the lower extremities. It is considered a form of thrombotic vasculopathy, leading to occlusion of small dermal blood vessels and tissue necrosis.

Pathophysiology[edit | edit source]

Livedoid vasculopathy is a non-inflammatory thrombotic vasculopathy involving occlusion of small dermal blood vessels. The underlying mechanisms include:

Common laboratory findings in LV patients may include:

Clinical Features[edit | edit source]

Livedoid vasculopathy typically presents with:

The condition is chronic and relapsing, with ulcer healing leaving stellate white scars that are prone to recurrent breakdown.

Diagnosis[edit | edit source]

Diagnosis is based on:

Differential Diagnosis[edit | edit source]

Livedoid vasculopathy should be distinguished from:

Treatment and Management[edit | edit source]

Since LV is associated with microvascular thrombosis, treatment focuses on anticoagulation and improving circulation.

Pharmacologic Treatment[edit | edit source]

Lifestyle and Supportive Care[edit | edit source]

Prognosis[edit | edit source]

Livedoid vasculopathy is a chronic and relapsing condition with periods of remission and exacerbation. Some patients experience spontaneous resolution, while others require long-term anticoagulation to prevent ulcer recurrence.

Related pages[edit | edit source]

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