Trilaminar blastocyst

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Trilaminar blastocyst is a stage in the development of a mammalian embryo, occurring approximately five days after fertilization. The term "trilaminar" refers to the three layers that make up the blastocyst at this stage: the trophectoderm, the inner cell mass, and the blastocoel.

Etymology[edit | edit source]

The term "blastocyst" comes from the Greek words "blastos" (sprout) and "kystis" (cavity). "Trilaminar" is derived from the Latin "tri" (three) and "lamina" (layer).

Structure[edit | edit source]

The trilaminar blastocyst consists of three distinct parts:

  • Trophectoderm: This is the outer layer of the blastocyst. It will eventually form the placenta and other supporting tissues needed for fetal development within the uterus.
  • Inner cell mass: This group of cells is located inside the trophectoderm and will eventually form the embryo.
  • Blastocoel: This is a fluid-filled cavity inside the blastocyst.

Development[edit | edit source]

The development of the trilaminar blastocyst is a complex process that involves a series of cell divisions and changes in cell shape and function. It begins with the formation of a morula, a solid ball of cells. The morula then transforms into a blastocyst, with the formation of a central cavity (the blastocoel), and the differentiation of cells into the trophectoderm and the inner cell mass.

Clinical significance[edit | edit source]

The trilaminar blastocyst stage is critical for successful implantation in the uterus. It is at this stage that the embryo begins to attach to the uterine wall, a process that is essential for pregnancy to occur. In in vitro fertilization (IVF) procedures, embryos are often transferred to the uterus at the blastocyst stage to increase the chances of successful implantation.

See also[edit | edit source]

Trilaminar blastocyst Resources
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Contributors: Prab R. Tumpati, MD