Bolasterone
Anabolic steroid
Bolasterone[edit | edit source]
Bolasterone is a synthetic anabolic steroid that was first developed in the 1950s. It is known for its ability to promote muscle growth and increase strength, making it popular among bodybuilders and athletes. However, its use is associated with significant side effects and it is classified as a controlled substance in many countries.
Chemical Properties[edit | edit source]
Bolasterone is a derivative of testosterone, the primary male sex hormone and anabolic steroid. It is chemically known as 7_,17_-dimethyl-17_-hydroxyandrost-4-en-3-one. The addition of methyl groups at the 7_ and 17_ positions increases its oral bioavailability and anabolic activity.
Pharmacology[edit | edit source]
Bolasterone exhibits strong anabolic effects with moderate androgenic properties. It binds to the androgen receptors in muscle tissue, promoting protein synthesis and muscle growth. Its anabolic to androgenic ratio is higher than that of testosterone, making it more effective in building muscle mass with fewer androgenic side effects.
Medical Uses[edit | edit source]
Historically, bolasterone was used in the treatment of conditions such as muscle wasting and osteoporosis. However, due to its potential for abuse and adverse effects, its medical use has become limited.
Side Effects[edit | edit source]
The use of bolasterone can lead to a range of side effects, including:
- Liver toxicity due to its 17_-alkylated structure.
- Gynecomastia (development of breast tissue in men) due to its estrogenic activity.
- Acne and oily skin as a result of increased sebum production.
- Hair loss and hirsutism (excessive hair growth) due to its androgenic effects.
- Suppression of natural testosterone production, leading to hypogonadism.
Legal Status[edit | edit source]
Bolasterone is classified as a Schedule III controlled substance under the Anabolic Steroid Control Act in the United States. It is banned by most major sports organizations, including the World Anti-Doping Agency (WADA).
Related Compounds[edit | edit source]
Bolasterone is structurally related to other anabolic steroids such as methandrostenolone and oxandrolone. These compounds share similar anabolic properties but differ in their androgenic effects and side effect profiles.
See Also[edit | edit source]
Related Pages[edit | edit source]
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates, categories Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD