Branched chain amino acids
Branched-chain amino acids (BCAAs) are amino acids with aliphatic side-chains with a branch (a central carbon atom bound to three or more carbon atoms). Among the proteinogenic amino acids, there are three BCAAs: leucine, isoleucine, and valine.
Overview[edit | edit source]
BCAAs are among the nine essential amino acids for humans, accounting for 35% of the essential amino acids in muscle proteins and 40% of the preformed amino acids required by mammals. They are also used in medicine for a variety of purposes.
Structure[edit | edit source]
The three BCAAs are all essential amino acids, which means that they cannot be synthesized by the body and must be obtained from the diet. They are also the only amino acids that are not degraded in the liver. Instead, BCAAs are often broken down in muscle, thereby, they can play a role in energy production during exercise.
Functions[edit | edit source]
BCAAs play several important roles in the body. They are involved in the synthesis of other amino acids, and they can be used as an energy source by muscles. BCAAs also play a crucial role in protein synthesis and muscle growth. They can also help to prevent muscle wasting in people who are bedridden or ill.
Medical uses[edit | edit source]
In medicine, BCAAs are used for a variety of conditions. They are often used to treat liver disease, as they can help to prevent the buildup of harmful substances in the liver. BCAAs are also used to treat muscle wasting in people with diseases like cancer or AIDS.
Dietary sources[edit | edit source]
BCAAs are found in high amounts in protein-rich foods. Some of the best sources of BCAAs include meat, dairy products, and legumes. They can also be obtained from BCAA supplements, which are often used by athletes and bodybuilders to boost muscle growth and improve athletic performance.
See also[edit | edit source]
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Contributors: Prab R. Tumpati, MD