Bromazine

Bromazine is a pharmaceutical drug used in the treatment of various medical conditions. It belongs to the class of antipsychotic medications and is primarily used in the management of psychosis, including schizophrenia and manic phases of bipolar disorder.

Pharmacology

Bromazine works by blocking the action of dopamine, a neurotransmitter in the brain that affects thoughts and feelings. It has a high affinity for the D2 dopamine receptor and also has affinity for the D1 receptor. Bromazine also has anticholinergic and antihistaminic properties.

Uses

Bromazine is used in the treatment of a variety of conditions:

• Schizophrenia: Bromazine is used to manage the symptoms of schizophrenia, a mental disorder that affects a person's ability to think, feel, and behave clearly.

• Bipolar disorder: In the manic phase of bipolar disorder, bromazine can be used to control symptoms such as elevated mood, increased activity, and reduced need for sleep.

• Psychosis: Bromazine can be used to manage symptoms of psychosis, including hallucinations, delusions, and confused thinking.

Side Effects

Like all medications, bromazine can cause side effects. These may include drowsiness, dizziness, dry mouth, constipation, weight gain, and blurred vision. In rare cases, it can cause serious side effects such as tardive dyskinesia, a condition that affects the nervous system, and neuroleptic malignant syndrome, a rare but serious condition that can be life-threatening.

Precautions

Before starting treatment with bromazine, patients should discuss their medical history with their healthcare provider, especially any history of heart disease, liver disease, kidney disease, or seizures. Bromazine can interact with other medications, so patients should inform their healthcare provider of all the medications they are currently taking.

See Also

• Antipsychotic
• Dopamine
• Schizophrenia
• Bipolar disorder
• Psychosis