C6H11NO2

C6H11NO2 is the chemical formula for a compound known as leucine, which is an essential amino acid. Leucine is one of the nine essential amino acids in humans, meaning it cannot be synthesized by the body and must be obtained from the diet. It is encoded by the codons UUA, UUG, CUU, CUC, CUA, and CUG.

Structure and Properties

Leucine has a molecular weight of 131.17 g/mol. Its structure consists of a central carbon atom (the alpha carbon) bonded to an amino group (NH2), a carboxyl group (COOH), a hydrogen atom, and an isobutyl side chain, making it a branched-chain amino acid (BCAA). The chemical structure can be represented as:

 H2N-CH(C4H9)-COOH

Biological Role

Leucine plays a critical role in various metabolic pathways, including the synthesis of proteins and the regulation of blood sugar levels. It is also involved in the growth and repair of muscle and bone tissue. Leucine is particularly important in the process of muscle protein synthesis and is often included in dietary supplements for athletes and bodybuilders.

Sources

Leucine is found in high concentrations in foods such as meat, dairy products, soy products, beans, and legumes. It is also available in dietary supplements in the form of BCAA powders and capsules.

Metabolism

Leucine is metabolized primarily in the muscle and adipose tissue. It is converted into acetyl-CoA and acetoacetate, which can be used for energy production. The metabolism of leucine also produces HMG-CoA, a precursor for the synthesis of cholesterol and other isoprenoids.

Health Implications

Adequate intake of leucine is essential for maintaining muscle mass and overall health. Deficiency in leucine can lead to symptoms such as fatigue, muscle wasting, and impaired immune function. Conversely, excessive intake of leucine, particularly through supplements, can lead to toxicity and adverse effects on kidney function.

Related Pages

• Amino acid
• Branched-chain amino acid
• Protein synthesis
• Dietary supplement
• Metabolism