CDCP1

CDCP1 (CUB Domain Containing Protein 1) is a protein that in humans is encoded by the CDCP1 gene. It is a transmembrane protein that is involved in cell adhesion and signal transduction processes.

Function

CDCP1 is a cell surface protein that is phosphorylated upon DNA damage. It is known to interact with several other proteins, including Src family kinases and PKCδ, to mediate cell signaling pathways. The protein is also involved in the regulation of cell migration and cell adhesion, which are critical processes in tissue development and cancer metastasis.

Clinical significance

Alterations in the expression of CDCP1 have been associated with various types of cancer, including breast cancer, lung cancer, and prostate cancer. Overexpression of CDCP1 has been observed in many cancer types, suggesting a potential role in tumor progression and metastasis.

Research

Research into the function and role of CDCP1 in cancer is ongoing. Current studies are focused on understanding the molecular mechanisms underlying CDCP1-mediated cell signaling and its potential as a therapeutic target in cancer treatment.

See also

• CUB domain
• Cell adhesion
• Signal transduction
• Cancer metastasis