CGP-35348
GABA B receptor antagonist
| CGP-35348 | |
|---|---|
|
| |
| Identifiers
| |
| PubChem | 5311055
|
| ChemSpider | 4470910 |
| UNII | 0T493YFU8O |
| KEGG | D03457 |
| ChEMBL | 2106010 |
| Chemical data
| |
| Chemical formula | C10H22N1O2
|
| SMILES | C1CCC(CC1)C(CN)P(=O)(O)O
|
CGP-35348 is a compound that acts as a GABA B receptor antagonist. It is used in scientific research to investigate the role of GABA B receptors in various physiological and neurological processes.
Mechanism of Action[edit]
CGP-35348 works by inhibiting the action of gamma-Aminobutyric acid (GABA) at the GABA B receptor. This receptor is a G-protein coupled receptor that mediates slow and prolonged inhibitory signals in the central nervous system. By blocking this receptor, CGP-35348 can modulate neurotransmission and affect various neurological and psychiatric conditions.
Research Applications[edit]
CGP-35348 has been used in various preclinical studies to understand the role of GABA B receptors in anxiety, depression, epilepsy, and pain. It has also been investigated for its potential effects on cognition and memory.
Pharmacokinetics[edit]
The pharmacokinetics of CGP-35348 involve its absorption, distribution, metabolism, and excretion. Detailed studies on its bioavailability, half-life, and metabolic pathways are essential for understanding its potential therapeutic applications.
Safety and Toxicology[edit]
As with any pharmacological agent, the safety and toxicology profile of CGP-35348 is crucial. Studies typically focus on its LD50, potential side effects, and long-term impact on organ systems.
See Also[edit]
References[edit]
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