Cancer Investigation

From WikiMD's Wellness Encyclopedia

Cancer Investigation is a broad field of medical science that involves the study and research of cancer, a group of diseases characterized by the uncontrolled growth and spread of abnormal cells. The primary goal of cancer investigation is to understand the causes and development of cancer to improve diagnosis, treatment, and prevention strategies.

Overview[edit | edit source]

Cancer investigation encompasses a wide range of disciplines including biology, genetics, epidemiology, and clinical research. It involves the study of the molecular mechanisms of cancer, the identification of genetic and environmental risk factors, the development of new diagnostic tools and treatments, and the evaluation of their effectiveness in clinical trials.

Molecular and Cellular Biology[edit | edit source]

At the molecular and cellular level, cancer investigation focuses on understanding the changes that occur in cells that lead to the development of cancer. This includes the study of oncogenes, genes that have the potential to cause cancer, and tumor suppressor genes, which normally prevent cells from becoming cancerous. Researchers also investigate the role of DNA damage and repair, cell cycle control, and cell death in the development of cancer.

Genetics[edit | edit source]

Cancer investigation in the field of genetics involves the study of inherited cancer syndromes and the identification of cancer susceptibility genes. This research has led to the development of genetic testing for certain types of cancer, such as breast cancer and colorectal cancer, and has improved our understanding of the genetic factors that contribute to cancer risk.

Epidemiology[edit | edit source]

In epidemiology, cancer investigation involves the study of cancer patterns in different populations and the identification of environmental and lifestyle factors that increase cancer risk. This includes research on tobacco use, diet, physical activity, alcohol consumption, sun exposure, and occupational hazards.

Clinical Research[edit | edit source]

Clinical research in cancer investigation involves the development and testing of new cancer treatments and diagnostic tools. This includes clinical trials to evaluate the safety and effectiveness of new drugs, radiation therapy techniques, surgical procedures, and immunotherapies. Clinical research also involves the study of cancer survivorship, including the long-term effects of cancer treatment and the quality of life of cancer survivors.


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Contributors: Prab R. Tumpati, MD