Charles Scriver

Charles Scriver (born November 7, 1930) is a renowned geneticist and pediatrician from Canada. He is best known for his extensive research in genetic disorders, particularly inborn errors of metabolism.

Early Life and Education

Scriver was born in Montreal, Quebec, Canada. He completed his undergraduate studies at McGill University, where he also earned his medical degree in 1955. He then pursued his postgraduate training in pediatrics at the Harvard Medical School and the Children's Hospital Boston.

Career

Scriver returned to McGill University in 1961, where he established the DeBelle Laboratory in Biochemical Genetics. This was the first laboratory in Canada dedicated to the study of biochemical genetics and inborn errors of metabolism.

Scriver's research has significantly contributed to the understanding of several genetic disorders, including phenylketonuria (PKU), hypophosphatasia, and vitamin D-dependent rickets. He was instrumental in the implementation of newborn screening programs for PKU in Quebec, which has since been adopted worldwide.

Awards and Honors

Scriver has received numerous awards and honors for his contributions to genetics and pediatrics. These include the Wolf Prize in Medicine, the Gairdner Foundation International Award, and the Order of Canada. He is also a Fellow of the Royal Society of Canada and the Royal Society of London.

Legacy

Scriver's work has had a profound impact on the field of genetics and pediatrics. His research has not only improved the understanding of genetic disorders but also influenced public health policies and practices. He has authored several books and publications, including the definitive textbook on inborn errors of metabolism, "The Metabolic and Molecular Bases of Inherited Disease."