Clement Markert

Clement Markert 1991

Clement Lawrence Markert (April 11, 1917 – October 1, 1999) was an American biologist and geneticist known for his pioneering work in the field of developmental biology and biochemical genetics. He made significant contributions to the understanding of isozymes and their role in cell differentiation and development.

Early Life and Education

Clement Markert was born on April 11, 1917, in Las Animas, Colorado. He completed his undergraduate studies at University of Colorado and later earned his Ph.D. in biology from the Johns Hopkins University in 1942.

Career and Research

Markert's early research focused on the study of isozymes, which are different forms of an enzyme that catalyze the same reaction but differ in amino acid sequence. His work in this area helped to establish the concept of isozymes and their importance in genetics and developmental biology.

In the 1950s, Markert joined the faculty at Johns Hopkins University and later moved to Yale University, where he continued his research on isozymes. His studies demonstrated that isozymes could be used as markers for cell differentiation and tissue development. This work provided valuable insights into the mechanisms of gene expression and cellular differentiation.

Contributions to Science

Markert's research on isozymes had a profound impact on the field of biochemistry and genetics. He developed techniques for the separation and characterization of isozymes, which became essential tools for researchers studying enzyme function and genetic variation. His work also contributed to the understanding of metabolic pathways and their regulation in different tissues and organs.

Awards and Honors

Throughout his career, Clement Markert received numerous awards and honors for his contributions to science. He was elected to the National Academy of Sciences and received the Gairdner Foundation International Award for his pioneering work in biochemical genetics.

Personal Life

Clement Markert was married and had three children. He passed away on October 1, 1999, leaving behind a legacy of significant contributions to the fields of developmental biology and genetics.

Legacy

Markert's work on isozymes continues to influence research in biochemistry, genetics, and developmental biology. His contributions have paved the way for further studies on enzyme function, gene expression, and cell differentiation.

See Also

• Developmental biology
• Genetics
• Isozymes
• Cell differentiation
• Biochemical genetics