Clocinnamox

Clocinnamox is a drug that is used in scientific research. It acts as a potent and selective antagonist for the mu opioid receptor, and has been used to develop a variety of other compounds for further study.

Pharmacology

Clocinnamox has a high affinity for the mu opioid receptor, and acts as an antagonist at this site. This means that it blocks the effects of other drugs that activate this receptor, such as morphine and other opioids. It is highly selective for the mu receptor, with much lower affinity for the delta and kappa receptors.

Chemistry

Clocinnamox is a derivative of the opioid antagonist naloxone, and is structurally similar to this compound. It has a cinnamoyl group attached to the nitrogen atom of the naloxone molecule, which is thought to be responsible for its high affinity for the mu opioid receptor.

Use in research

Clocinnamox has been used in a variety of research studies to investigate the role of the mu opioid receptor in pain, addiction, and other processes. It has also been used to develop a range of other compounds for further study, including beta-funaltrexamine, naltrindole, and nor-binaltorphimine.

See also

• Opioid receptor
• Opioid antagonist
• Naloxone

Clocinnamox Resources
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