Cloticasone

Cloticasone is a corticosteroid used in the treatment of various inflammatory and allergic conditions. It is a synthetic glucocorticoid, a class of steroid hormones that are produced in the adrenal gland. Cloticasone is primarily used in the form of an inhaler for the treatment of asthma and chronic obstructive pulmonary disease (COPD). It can also be used topically for skin conditions such as eczema and psoriasis.

Mechanism of Action

Cloticasone works by reducing inflammation in the body. It does this by inhibiting the release of inflammatory mediators such as histamine and prostaglandins. This results in a decrease in swelling, redness, and pain associated with inflammation.

Uses

Cloticasone is used in the treatment of a variety of conditions, including:

• Asthma: Cloticasone is used as a maintenance therapy in the long-term control of asthma. It helps to prevent and control symptoms such as wheezing and shortness of breath.

• Chronic Obstructive Pulmonary Disease (COPD): Cloticasone is used to decrease the frequency and severity of exacerbations and improve health status in patients with COPD.

• Eczema and Psoriasis: Topical forms of cloticasone can be used to reduce the inflammation and itching associated with these skin conditions.

Side Effects

Like all medications, cloticasone can cause side effects. These may include:

• Throat irritation
• Hoarseness or voice changes
• Cough
• Dry mouth or nose
• Headache

More serious side effects can include:

• Vision changes
• Swelling ankles or feet
• Increased thirst or urination
• Weight gain

Precautions

Before using cloticasone, patients should inform their healthcare provider if they have any allergies, or if they have a history of tuberculosis, herpes of the eye, or other infections.

See Also

• Corticosteroid
• Glucocorticoid
• Asthma
• Chronic Obstructive Pulmonary Disease
• Eczema
• Psoriasis