Cryofibrinogenemia
Cryofibrinogenemia is a rare blood disorder characterized by the presence of cryofibrinogen in the blood. Cryofibrinogen is a type of protein that becomes insoluble at low temperatures. This condition can lead to various symptoms, including skin ulcers, pain, and gangrene.
Symptoms[edit | edit source]
The symptoms of cryofibrinogenemia can vary widely, but often include:
Causes[edit | edit source]
The exact cause of cryofibrinogenemia is unknown. However, it is often associated with other conditions, such as:
Diagnosis[edit | edit source]
Diagnosis of cryofibrinogenemia is based on the detection of cryofibrinogen in the blood. This is usually done through a blood test that involves cooling the blood sample to see if cryofibrinogen forms.
Treatment[edit | edit source]
Treatment for cryofibrinogenemia typically involves addressing the underlying condition. This may include:
- Antiviral therapy for hepatitis C
- Immunosuppressive therapy for autoimmune diseases
- Chemotherapy or radiation therapy for malignancies
- Antibiotics for infections
In some cases, plasmapheresis may be used to remove cryofibrinogen from the blood.
See also[edit | edit source]
| Cryofibrinogenemia Resources | |
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Contributors: Prab R. Tumpati, MD
