Cutaneous ciliated cyst

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Cutaneous ciliated cyst is a rare type of cyst that typically occurs on the lower extremities of young women. The term "cutaneous" refers to the skin, and "ciliated" describes the cyst's lining, which contains cilia - hair-like structures that can move back and forth. These cysts are benign (non-cancerous) and are thought to arise from ectopic ciliated epithelium, possibly due to embryonic remnants or metaplastic processes.

Etiology and Pathogenesis[edit | edit source]

The exact cause of cutaneous ciliated cysts is not well understood. However, two main theories have been proposed to explain their origin. The first theory suggests that these cysts are the result of metaplastic changes in the cells of the skin, where the normal skin cells transform into a type of cell not typically found at that location, in this case, ciliated cells. The second theory posits that these cysts are of Müllerian duct origin, arising from ectopic Müllerian tissue that has been misplaced during embryonic development. Müllerian ducts are precursors to the female reproductive tract, which explains why these cysts predominantly occur in women.

Clinical Presentation[edit | edit source]

Cutaneous ciliated cysts usually present as solitary, well-defined, mobile subcutaneous nodules. They are most commonly found on the lower extremities, particularly on the thighs or legs, but can also occur in other areas such as the buttocks or vulva. These cysts are generally asymptomatic, although some patients may experience discomfort or pain if the cyst becomes inflamed or infected.

Diagnosis[edit | edit source]

The diagnosis of a cutaneous ciliated cyst is primarily based on histological examination. Imaging techniques such as ultrasound or MRI may be used to assess the cyst's size and depth, but definitive diagnosis requires tissue biopsy. Histologically, these cysts are characterized by a lining of ciliated columnar epithelium, which is unusual for skin lesions and helps distinguish them from other types of cysts.

Treatment[edit | edit source]

The standard treatment for cutaneous ciliated cysts is surgical excision. Complete removal of the cyst is necessary to prevent recurrence. Since these cysts are benign, the prognosis after removal is excellent, with minimal risk of complications.

Epidemiology[edit | edit source]

Cutaneous ciliated cysts are rare, with a higher prevalence in young adult women. There is limited data on their incidence and prevalence due to the rarity of these cysts.

Conclusion[edit | edit source]

Cutaneous ciliated cysts are an uncommon but interesting type of skin cyst, primarily affecting young women. Their unique histological features and proposed origins from ectopic or metaplastic ciliated epithelium make them a notable subject for study in dermatology and pathology. Although benign, proper diagnosis and treatment are essential to alleviate any discomfort and prevent potential complications.

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Contributors: Prab R. Tumpati, MD