DUXAP8
DUXAP8 is a long non-coding RNA gene that is associated with various types of cancer. It is located on chromosome 20q11.21 and is highly expressed in several types of tumors, including lung cancer, gastric cancer, and colorectal cancer.
Function[edit | edit source]
The exact function of DUXAP8 is not fully understood. However, it is believed to play a role in the regulation of gene expression. It has been suggested that DUXAP8 may act as a molecular sponge, binding to and sequestering certain microRNAs, thereby preventing them from regulating their target genes. This could potentially lead to the overexpression of certain oncogenes, promoting tumor growth and progression.
Clinical significance[edit | edit source]
DUXAP8 has been identified as a potential biomarker for several types of cancer. High levels of DUXAP8 expression have been associated with poor prognosis in patients with lung cancer, gastric cancer, and colorectal cancer. In addition, DUXAP8 may also serve as a potential therapeutic target. In vitro studies have shown that silencing DUXAP8 can inhibit tumor growth and induce apoptosis in cancer cells.
Research[edit | edit source]
Research into the role of DUXAP8 in cancer is ongoing. Current areas of focus include elucidating the exact mechanisms by which DUXAP8 promotes tumor growth and progression, identifying the specific microRNAs that DUXAP8 interacts with, and exploring the potential of DUXAP8 as a therapeutic target.
See also[edit | edit source]
References[edit | edit source]
Template:Genes on human chromosome 20
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