DUXAP8

DUXAP8 is a pseudogene located on chromosome 22 in humans. It is part of the double homeobox gene family, which is known for its role in gene regulation and developmental processes.

Function

DUXAP8 is classified as a pseudogene, meaning it is a non-functional segment of DNA that resembles a gene. Pseudogenes like DUXAP8 are often considered "genomic fossils" that provide insights into the evolutionary history of genomes. Although DUXAP8 itself does not encode a functional protein, it may have regulatory roles or be involved in gene expression modulation.

Clinical Significance

Research has suggested that DUXAP8 may be involved in certain cancers. Studies have shown that the expression of DUXAP8 is upregulated in various tumor types, including lung cancer and gastric cancer. It is hypothesized that DUXAP8 may contribute to tumorigenesis by affecting cell proliferation and apoptosis.

Research

Ongoing research is focused on understanding the precise mechanisms by which DUXAP8 influences cancer progression. Investigations are also exploring the potential of targeting DUXAP8 for therapeutic purposes, aiming to develop novel cancer treatments.

See Also

• Pseudogene
• Gene expression
• Chromosome 22
• Cancer

External Links

• DUXAP8 Gene - NCBI
• DUXAP8 - GeneCards